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Biomaterials: A Basic Introduction 1st Edition
출판사 : CRC
저 자 : Qizhi Chen
ISBN : 9781138749665
발행일 : 2018-5
도서종류 : 외국도서
발행언어 : 영어
페이지수 : 706
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   Biomaterials: A Basic Introduction 1st Edition 목차
Table of Contents

Part I

Biomaterials Science

Biomaterials Science and Engineering

Learning Objectives

Materials Science and Engineering

Multilevels of Structure and Categorization of Materials

Four Categories of Materials

Definitions of Biomaterials, Biomedical Materials, and Biological Materials

Biocompatibility

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Toxicity and Corrosion

Learning Objectives

Elements in the Body

Biological Roles and Toxicities of Trace Elements

Selection of Metallic Elements in Medical-Grade Alloys

Corrosion of Metals

Environment inside the Body

Minimization of Toxicity of Metal Implants

Chapter Highlights

Laboratory Practice 1

Simple Questions in Class

Problems and Exercises

Advanced Topic: Biological Roles of Alloying Elements

Bibliography

Mechanical Properties of Biomaterials

Learning Objectives

Role of Implant Biomaterials

Mechanical Properties of General Importance

Hardness

Elasticity: Resilience and Strechability

Mechanical Properties Terms Used in the Medical Community

Failure

Essential Mechanical Properties of Orthopedic Implant Biomaterials

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Metallic Biomaterials in Orthopedic Implants

Learning Objectives

Development of Metallic Biomaterials

Stainless Steels

Cobalt-Based Alloys

Titanium Alloys

Comparison of Stainless Steels, Cobalt, and Titanium Alloys

Summary and Remarks

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Metallic Biomaterials: Miscellaneous Others

Learning Objectives

Dental Materials

NiTi Shape-Memory Alloys

Other Clinically Applied Metallic Materials

New Metallic Materials: Magnesium Alloys

Chapter Highlights

Laboratory Practice 2

Simple Questions in Class

Problems and Exercises

Bibliography

Bioinert Ceramics

Learning Objectives

Overview of Bioceramics

Inert Bioceramics: Al2O3

Inert Bioceramics: ZrO2

Two Types of Joints

Summary and Remarks on Al2O3 and ZrO2

Dental Ceramics

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Advanced Topic: Total Joint Replacement

Bibliography

Bioactive and Bioresorbable Ceramics

Learning Objectives

Overview of Surface Bioactive and Bulk Degradable Ceramics

Calcium Phosphates and Hydroxyapatite

Bioactive Glasses

Bioactive Glass-Ceramics

Bone-Bonding Mechanisms

Biodegradable Ceramics

Chapter Highlights

Laboratory Practice 3

Simple Questions in Class

Problems and Exercises

Advanced Topic: Bioceramic Scaffolds for Bone Tissue Engineering

Bibliography

Polymeric Biomaterials: Fundamentals

Learning Objectives

Basic Concepts on Polymers

Overview of Polymeric Biomaterials

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Advanced Topic: Polymers and Polymer Scaffolds for Soft Tissue Engineering

Bibliography

Bioinert Polymers

Learning Objectives

Polyolefin

Poly(Ethylene Terephthalate)

Acrylate Polymer

Fluorocarbon Polymers

Silicone

Polyurethane

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Advanced Topic: Properties and Applications of Polyurethane as Biomaterials

Bibliography

Bioresorbable Polymers

Learning Objectives

Biodegradation of Polymers

Polyesters: PGA, PLA, and PCL

Polyesters: PHA

Elastomeric Polyester: Poly(Polyol Sebacate)

Polyether: Poly(Ethylene Glycol)

Polyamide

Surface-Erodible Polymers

Biological Polymers

Chapter Highlights

Simple Questions in Class

Problems and Exercises

Laboratory Practice 4

Advanced Topic: Natural Polymers: Resilin, Silk, and Gluten

Bibliography

Composite Biomaterials

Learning Objectives

Overview of Composites

Natural Composites: Bone

Dental Composites

Artificial Bone

Chapter Highlights

Laboratory Practice 5

Simple Questions in Class

Problems and Exercises

Advanced Topic: Development of Artificial Bone: Composites and Scaffolds

Bibliography

Part II

Medical Science

Medicine and Medical Science

Learning Objectives

Medicine and Medical Science

Medical Science versus Materials Science

Learning Goals of Part II

Chapter Highlights

Activity

Bibliography

Image Links

Simple Questions in Class

Problems and Exercises

Human Anatomy And Diseases I: Integumentary, Skeletal, Muscular, Nervous, and Endocrine Systems

Learning Objectives

Integumentary System

Skeletal System

Muscular System

Nervous System

Endocrine System

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Advanced Topic: Biomaterial Challenges in Bone Tissue Engineering

Bibliography

Human Anatomy And Diseases II: Cardiovascular System

Learning Objectives

Anatomy and Functions of the Cardiovascular System

Cardiovascular Disease

Cardiac Performance: P–V Loop

Current Therapies for Heart Disease

Alternative Treatments and Application of Biomaterials

Artificial Blood Vessels

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Human Anatomy And Diseases III: Respiratory, Lymphatic, Digestive, Urinary, and Reproductive Systems

Learning Objectives

Respiratory System

Lymphatic System

Digestive System

Urinary System

Reproductive System

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Cells and Biomolecules

Learning Objectives

Introduction

Cell Biochemistry and Biosynthesis

Cell Structure

Transport across Plasma Membranes

Cell Proliferation

Cell Differentiation and Stem Cells

Chapter Highlights

Activities

Advanced Topic: Cell Therapy to Treat Cardiac Disease

Strategies to Address Immune Rejection in Cells

Summary of Cell-Based Therapies and Their Limitations

Simple Questions in Class

Problems and Exercises

Bibliography

Histology and Tissue Properties I: Epithelial, Neuronal, and Muscle Tissue

Learning Objectives

Introduction

Epithelium

Muscular Tissue

Nervous Tissue

Chapter Highlights

Activities

Advanced Topic: Properties of Proteins in Mammalian Tissues

Simple Questions in Class

Problems and Exercises

Bibliography

Histology and Tissue Properties II: Connective Tissues

Learning Objectives

Overview of Connective Tissues

Types of Connective Tissue

Connective Tissue Proper (Skin, Tendon, Ligament)

Mechanical Properties of Structural Proteins

Cartilage

Bone

Chapter Highlights

Laboratory Practice 6

Simple Questions in Class

Problems and Exercises

Bibliography

Immune System and Body Responses to Biomaterials

Learning Objectives

Immune System

Tissue Response to Injuries

Body Response to Implants

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Evaluation of Biomaterials

Learning Objectives

Overview of Biomaterials Evaluation

Standards

Toxicological Evaluation

Cytotoxicity Testing

Evaluation in Animals

Chapter Highlights

Laboratory Practice 7

Case Study: Evaluation of Heart Patch in Rats

Simple Questions in Class

Problems and Exercises

Bibliography

Regulation of Medical Devices

Learning Objectives

Regulations versus Standards

Medical Devices

Preclinical Testing

Clinical Trials

Development of Medical Devices and Possible Career Opportunities

Chapter Highlights

Activities

Simple Questions in Class

Problems and Exercises

Bibliography

Index
   도서 상세설명   



Biomaterials: A Basic Introduction is a definitive resource for students entering biomedical or bioengineering disciplines. This text offers a detailed exploration of engineering and materials science, and examines the boundary and relationship between the two. Based on the author’s course lecture notes and many years of research, it presents students with the knowledge needed to select and design biomaterials used in medical devices. Placing special emphasis on metallic, ceramic, polymeric, and composite biomaterials, it explains the difference between materials science and materials engineering, introduces basic concepts and principles, and analyzes the critically important properties of biomaterials.

Explains Complex Theories Using Aspects of Daily Life

This text provides an appropriate balance between depth and broadness of coverage, and offers an understanding of the most important concepts and principles to students from a wide academic spectrum. It delivers the science of biomaterials in laymen terms, from a material standpoint, as well as a clinical applications point of view. It equips students majoring in materials science/engineering with knowledge on the fundamentals of how biomaterials behave at a biological level, and provides students majoring in medicine with information that is generally unavailable in traditional medical courses. The authors incorporate learning objectives at the beginning of each chapter, as well as chapter highlights, problems, and exercises at the end of each chapter. In addition, they present objectives, suggested activities, and reference material for further reading.

Contains an overview of medical science vis-à-vis materials science, describes anatomy, histology, and cell biology
Highlights health issues and diseases where biomaterials can easily find medical applications
Presents knowledge of the relationship between the biomaterials and the living body
Evaluates medical devices and looks into their respective regulations

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