Platelets > 생명과학

Table of Contents
Foreword: A Brief and Highly Selective History of Ideas About Platelets in Health and Disease. Barry S. Coller

Part One: Biology The Evolution of Mammalian Platelets. Jack Levin
Megakaryocyte Development and Platelet Formation. Joseph E. Italiano, Jr., John H. Hartwig
Platelet Structure. John H. Hartwig
Platelet Turnover and Aging. Peter Batar, George L. Dale
Platelet Receptors. Kenneth J. Clemetson
The GPIb-IX-V Complex. Jos?A. L?ez, Michael C. Berndt
Integrin aIIb face=\"symbol\">b3. Takaaki Hato, Mark H. Ginsberg,
Sanford J. Shattil
Thrombin Receptors. Addison R. Tolentino, Wadie F. Bahou
P-Selectin/PSGL-1 and Other Interactions Between Platelets, Leukocytes, and Endothelium. Rodger P. McEver
Platelet Polymorphisms. Vahid Afshar-Kharghan, Paul F. Bray
Platelet Secretion. Guy L. Reed
Signal Transduction During the Initiation, Extension, and Perpetuation of Platelet Plug Formation.
Donna Woulfe, Jing Yang, Nicolas Prevost, Peter J. O'Brien, Lawrence F. Brass
Platelet Thrombus Formation in Flowing Blood. Brian Savage, Zaverio M. Ruggeri
Interactions Between Platelets and the Coagulation System. Beth A. Bouchard, Saulius Butenas, Kenneth G. Mann, Paula B. Tracy
Platelet-Derived Microparticles. Rienk Nieuwland, Augueste Sturk Platelet Function in the Newborn. Sara J. Israels


Part Two: Tests of Platelet Function
Platelet Count. Majed Refaai, Michael Laposata
The Bleeding Time. Stuart E. Lind
Platelet Aggregation. Majed Refaai, Michael Laposata
Flow Cytometry. Alan D. Michelson, Marc R. Barnard, Lori A. Krueger, A. L. Frelinger III, Mark I. Furman
Ultegra Rapid Platelet Function Analyzer. Steven R. Steinhubl, Dean J. Kereiakes
Platelet Function Analyzer (PFA)-100. John L. Francis
Cone and Plate(let) Analyzer. David Varon, Naphtali Savion
Perfusion Chambers. Philip G. de Groot, Jan J. Sixma
Animal Models. David H. Lee, Morris A. Blajchman


Part Three: The Role of Platelets in Disease
Atherosclerosis and Coronary Artery Disease. Pascal J. Goldschmidt, Nueza Lopes, Lawrence E. Crawford
Ischemic Cerebrovascular Disease. Gregory J. del Zoppo
Peripheral Vascular Disease. Michael J. Rohrer
Diabetes Mellitus. Diethelm Tschoepe, Barbara Houtermans
Renal Disease. Jeffrey L. Barnes
Inflammation. Matthias H.F. Klinger
Antimicrobial Host Defense. Michael R. Yeaman, Arnold S. Bayer
Tumor Growth and Metastasis. Simon Karpatkin
Alzheimer Disease. Qiao-Xin Li, Konrad Beyreuther, Colin L. Masters
Psychiatric Disorders. George N. M. Gurguis, A. John Rush


Part Four: Disorders of Platelet Number and Function
The Clinical Approach to Disorders of Platelet Number and Function. Alan D. Michelson
Immune Thrombocytopenic Purpura. James B. Bussel
HIV-1-related Thrombocytopenia. Simon Karpatkin
Heparin-induced Thrombocytopenia. Beng H. Chong
Drug-induced Thrombocytopenia. Richard H. Aster
Thrombotic Thrombocytopenic Purpura and Hemolytic-Uremic Syndrome. Joel L. Moake
Thrombocytopenia in Pregnancy. Howard H.W. Chan, Karamjit Gill, John G. Kelton
Thrombocytopenia in the Newborn. Irene A. G. Roberts, Neil A. Murray
Pseudothrombocytopenia. Nicola Bizzaro
Thrombocytosis and Essential Thrombocythemia. Ayalew Tefferi
Inherited Disorders of Platelet Function. Alan T. Nurden, Paquita Nurden
Acquired Disorders of Platelet Function. A. Koneti Rao
Cardiopulmonary Bypass. Brian R. Smith, Henry M. Rinder, Christine S. Rinder


Part Five: Pharmacology: Antiplatelet Therapy
Aspirin. Eric H. Awtry, Joseph Loscalzo
GPIIb-IIIa Antagonists. Ramtin Agah, Edward F. Plow, Eric J. Topol
Clopidogrel and Ticlopidine. Ronan Curtin, Dermot Cox, Desmond J. Fitzgerald
Dipyridamole. Wolfgang G. Eisert
Cilostazol. Yasuo Ikeda, Toshiki Sudo, Yukio Kimura


Part Six: Pharmacology: Therapy to Increase Platelet Numbers and/or Function
Thrombopoietin. David J. Kuter
Interleukin 11. Ullrich Schwertschlag, Katherine J. Turner, Paul Schendel
Desmopressin. Marco Cattaneo, P. Mannuccio Mannucci
Factor VIIa. Man-Chiu Poon


Part Seven: Transfusion Medicine
Platelet Storage and Transfusion. Peter L. Perrotta, Edward L. Snyder
Platelet Transfusion in Infants and Children. Anne L. Angiolillo, Naomi L. C. Luban
Platelet Substitutes and Novel Methods of Platelet Preservation. David H. Lee, Morris A. Blajchman


Part Eight: Gene Therapy
Gene Therapy for Platelet Disorders. David A. Wilcox, Gilbert C. White II