Introductory Text to Bioengineering, 2/Ed > 생명과학

Contributors ix

Preface xvii

Acknowledgments xix

Section I Introductory Chapters

Chapter 1 Overview Shu Chien 3

Chapter 2 Perspectives of Biomechanics Yuan-Cheng B. Fung Wei Huang 13

Section II Cardiovascular Bioengineering

Chapter 3 Cardiac Electromechanics in the Healthy Heart Roy C. P. Kerckhoffs Andrew D. McCulloch 37

Chapter 4 Cardiac Biomechanics and Disease Jeffrey H. Omens 53

Chapter 5 Bioengineering Solutions for the Treatment of Heart Failure John T. Watson Shu Chien 69

Chapter 6 Molecular Basis of Modulation of Vascular Functions by Mechanical Forces Shu Chien 79

Chapter 7 Autoregulation of Blood Flow: Examining the Process of Scientific Discovery Paul C. Johnson 99

Section III Blood Cell Bioengineering

Chapter 8 Molecular Basis of Cell and Membrane Mechanics Lanping Amy Sung 117

Chapter 9 Cell Activation in the Circulation: The Auto-Digestion Hypothesis Geert W. Schmid-Schonbein 131

Chapter 10 Blood Substitutes and the Design of Oxygen Non-Carrying and Carrying Fluids Marcos Intaglietta 149

Section IV Respiratory-Renal Bioengineering

Chapter 11 Analysis of Human Pulmonary Circulation: A Bioengineering Approach Wei Huang Michael R. T. Yen Qinlian Zhou 163

Chapter 12 Pulmonary Gas Exchange Peter D. Wagner 181

Chapter 13 Engineering Approaches to Understanding the Kidney Scott C. Thomson 209

Section V Tissue Engineering and Regenerative Medicine

Chapter 14 Skeletal Muscle Tissue Bioengineering Richard L. Lieber Samuel R. Ward 225

Chapter 15 Multi-Scale Biomechanics of Articular Cartilage Won C. Bae Robert L. Sah 243

Chapter 16 Design and Development of an In Vivo Force-Sensing Knee Prosthesis Darryl D. D\'Lima Peter C. Y.Chen 261

Chapter 17 The Implantable Glucose Sensor in Diabetes: A Bioengineering Case Study David A. Gough 279

Chapter 18 Stem Cells in Regenerative Medicine Shu Chien Lawrence S. B. Goldstein 291

Section VI Nanoscience and Nanotechnology

Chapter 19 Engineering Compounds Targeted to Vascular Zip Codes Erkki Ruoslahti 313

Chapter 20 The Structure of the Central Nervous System and Nanoengineering Approaches for Studying and Repairing It Gabriel A. Silva 327

Chapter 21 Cellular Biophotonics: Laser Scissors (Ablation) Michael W. Berns 353

Chapter 22 Microelectronic Arrays: Applications from DNA Hybridization Diagnostics to Directed Self-Assembly Nanofabrication Michael J. Heller Dietrich Dehlinger 369

Section VII Genomic Engineering and Systems Biology

Chapter 23 Systems Biology: A Four-Step Process Jennifer L. Reed Bernhard O. Palsson 387

Chapter 24 Bioinformatics and Systems Biology: Obtaining the Design Principles of Living Systems Shankar Subramaniam 401

Chapter 25 Synthetic Biology: Bioengineering at the Genomic Level Natalie Ostroff Mike Ferry Scott Cookson Tracy Johnson Jeff Hasty 427

Chapter 26 Network Genomics 453 Trey Ideker

Chapter 27 Genomes, Genomic Technologies and Medicine Xiaohua Huang 473

Section VIII Socio-Economical Aspects of Bioengineering

Chapter 28 Ethics for Bioengineers Michael Kalichman 489

Chapter 29 Opportunities and Challenges in Bioengineering Entrepreneurship Jen-Shih Lee 507

Chapter 30 How to Move Medical Devices from Bench to Bedside Paul Citron 521

Index 533