Introductory Immunology: Basic Concepts for Interdisciplinary Applications > 자연과학 특가할인

Preface
Dedication
Preface
Acknowledgments
Chapter 1. A Functional Overview of the Immune System and Immune Components
Immune Homeostasis
Self vs. Non-Self
Innate and Adaptive Immunity
Anatomy of the Immune System
Cells of the Immune System
First Line Defenders: The Myeloid Cells
Adaptive Avengers: The Lymphoid Cells
Lymphocytes
Cluster of Differentiation
Summary
Chapter 2. The Inflammatory Response
Inflammation
Initiation of the Inflammatory Response
Role of Antibodies in Inflammation
Biological Functions of Complement
Activation and Directed Migration of Leukocytes
Pathogen Recognition and Cytokine Signaling
Feedback and Adaptation from a Distance
Summary
Chapter 3. The B Lymphocyte and the Humoral Response
B Lymphocytes Produce Antibodies
Structural Characteristics of Immunoglobulins
Immunoglobulin Nomenclature
Biologic Properties of Antibody Isotypes
Kinetics of Antibody Response
Membrane-Bound Immunoglobulin
Development of B Cells
Gene Recombination
Development and Selection of Mature B Cells
Activation and Differentiation of B Cells
Summary
Chapter 4. T Lymphocytes: Ringleaders of Adaptive Immune Function
T Lymphocytes: Specific and Long-Lasting Immunity
The T Cell Receptor
T Cell Development
Antigen Recognition by T Cells: Requirement of Major Histocompatability Molecules
T Lymphocyte Functions
Events Involved in T Lymphocyte Activation
Role of T Cells in B Cell Activation
Cytotoxic T Cell Effectors
Innate Lymphocytes and Superantigens
Summary
Chapter 5. How We Defend Against Infectious Agents
Immune Homeostasis and Pathogenic Organisms
Major Immune Defense Mechanisms Against Pathogens
Physical Barriers to Infection
Bacterial Infections
Mycobacterial Infections
Viral Infections
Human Immunodeficiency Virus
Parasitic Infections (Helminths)
Fungal Infections
Evasion of Immune Response
Summary
Chapter 6. Basic Disorders of Immune Function
Immunodeficiency Disorders
Genetic Basis for Primary Immunodeficiency
Innate Deficiencies
Adaptive Immune Disorders
Treatment of Immunodeficiency Diseases
Immunodeficiency as a Predisposition to Disease
Summary
Chapter 7. Autoimmunity: Regulation of Response to Self
Homeostasis, Immune Regulation, and Autoimmunity
Tolerance to Self
Etiology of Autoimmune Disease
Role of Autoantibodies and Self-Reactive T Lymphocytes in Autoimmune Disorders
Laboratory Tests for Autoimmunity
Targeted Therapeutics
Summary
Chapter 8. The Immune Hypersensitivities
The Hypersensitive Disorders
Type I Hypersensitivity: IgE-Mediated Immediate Hypersensitivity
Type II Hypersensitivity: Antibody-Mediated Cytotoxic Hypersensitivity
Type III Hypersensitivity: Immune Complex-Mediated Hypersensitivity
Type IV Hypersensitivity: Delayed-Type (Cell-Mediated) Hypersensitivity
Alternate Hypersensitivity Classifications
Summary
Chapter 9. Vaccines and Immunotherapy
Principles of Vaccination
Basic Concepts of Protective Immunization
Types of Immunizations
Age and Timing of Immunizations
Passive Immunization
Therapeutic Uses of Immunoglobulins
Other Ways of Modifying Immunity
Summary
Chapter 10. Cancer Immunology
Understanding Immune Defenses Against Cancers
Tumor Antigens
Effector Mechanisms in Tumor Immunity
Escape Mechanisms of Tumor Elimination
Tumors of the Immune System
Immunodiagnosis and Immunotherapy
Summary
Chapter 11. Transplantation Immunology
Transplantation Defined
Tissue Histocompatibility
Allograft Rejection
Graft-Versus-Host Disease
Pre-Transplantation Histocompatibility Evaluation
Immunosuppressive Drugs to Prevent Allograft Rejection
Summary
Chapter 12. Assessment of Immune Parameters and Immunodiagnostics
Antibody–Antigen Reactions
Secondary Manifestations of Antibody–Antigen Binding
Solid-Phase Precipitation Assays
Immunoassays
Detection of Cellular Antigens
Assays to Determine Immune Function
Other Tools to Measure Immunological Status
Summary
Acknowledgment
Glossary